In a 2008 study involving 25 healthy women aged 45-55 years old, results suggest that coenzyme Q10 (CoQ10) supplementation may exert anti-aging effects.

The activity of ECTO-NOX is age-related and increases with increasing age. The participants were assigned to an active (n=10; received 180 mg (3 x 60mg) of CoQ10 daily) or control group (n=15; no supplementation), for a period of 28 days. Serum, saliva and perspiration levels of age-related NOX were determined at 7, 14, and 28 days.

With all three bio-fluids, NOX activity reduced by 25-30% compared to baseline in the CoQ10 supplemented group alone. Thus, the results of this study suggest that CoQ10 supplementation may exert an anti-aging effect.

Reference: "Supplementation with CoQ10 lowers age-related (ar) NOX levels in healthy subjects," Morre DM, Kern D, et al, Biofactors, 2008; 32(1-4): 221-30. (Address: Department of Foods and Nutrition, Purdue University, West Lafayette, IN, USA).