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Ubiquinone and Ubiquinol What are the differences?

Ubiquinone and Ubiquinol are Redox compounds.

Ubiquinone is the fully oxidized form – the form generally sold commercially. Once ingested and absorbed in the body – more than 90% of the ingested Ubiquinone is converted into its “active” antioxidant form called Ubiquinol.

More than 90% of the circulating CoQ10 in our body is present as Ubiquinol. The body has reductase enzymes which take the ingested CoQ10 in food and supplements and convert most of it into Ubiquinol.

Research, (in animals and humans), has shown Ubiquinol to be absorbed better than Ubiquinone. Therefore, Ubiquinol might afford an advantage over ubiquinone in individuals who do not absorb regular CoQ10 from supplements too well. However, there are no studies to show the superiority of unsolubilized ubiquinol over Q-Gel® CoQ10, HydroQSorb® CoQ10, (as ChewQ® or H2Q CoQ10) or Liquid Q®..

There are a couple of studies sponsored by Tishcon which clearly show the superiority of solubilized Ubiquinol over Ubiquinone in dogs and also in humans. However, there are no solublized Ubiquinol products commercially available at the present time – EXCEPT for LiQ-Nol CoQ10 with Ubiquinol the “active” Coq10 and QuinoGel® Solubilized Ubiquinol CoQ10 (Hydrosoluble™ Kaneka QH™)from Tishcon.